Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534636 | 0.92 | CHKA (0.68) | CHKATP53MAPTPOLBGLA | |
| SCHEMBL2404836 | 0.91 | CHKA (0.57) | CHKATP53MAPTPOLBFPR2 | |
| SCHEMBL2535284 | 0.89 | CHKA (0.58) | CHKATP53MAPTTSHRPRMT5 | |
| SCHEMBL2433374 | 0.87 | FPR2 (0.56) | CHKATP53MAPTPOLBFPR2 | |
| SCHEMBL2533819 | 0.85 | CHKA (0.58) | CHKATP53MAPTTSHRLMNA | |
| SCHEMBL2530593 | 0.84 | CHKA (0.70) | CHKATP53MAPTPOLBFPR2 | |
| SCHEMBL2403608 | 0.83 | TP53 (0.55) | CHKATP53MAPTFPR2FPR1 | |
| SCHEMBL2402568 | 0.82 | CHKA (0.56) | CHKATP53MAPTPOLBLMNA | |
| SCHEMBL2406353 | 0.82 | MAPT (0.56) | CHKATP53MAPTPOLBFPR2 | |
| SCHEMBL2534523 | 0.81 | CHKA (0.68) | CHKATP53MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110257211-A1 | Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics | ADVANCED CANCER THERAPEUTICS, LLC (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257211-A1 | Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics | ADVANCED CANCER THERAPEUTICS, LLC (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257211-A1 | Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics | ADVANCED CANCER THERAPEUTICS, LLC (US) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257211-A1 | Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics | CHKA, CHKB, CEPT1 | CHKA 1/4885TP53 1116/4885MAPT 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.