Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15018821 | 0.84 | CHEK1 (0.35) | SMN1; SMN2ALDH1A1GAATSHRCHEK1 | |
| SCHEMBL28397444 | 0.84 | BCL9 (0.38) | KMT2AHDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25320420 | 0.83 | KMT2A (0.37) | KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28559470 | 0.82 | BCL9 (0.37) | KMT2AHDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25322244 | 0.82 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL7390728 | 0.80 | ACHE (0.43) | KMT2AHDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25322639 | 0.80 | NAMPT (0.37) | HDAC1SMN1; SMN2KDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL28408986 | 0.80 | KCNH2 (0.33) | KMT2ASMN1; SMN2KDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28159059 | 0.79 | ACHE (0.42) | KMT2AHDAC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25319801 | 0.75 | AAK1 (0.35) | KMT2ASMN1; SMN2GAASLC2A1SLC2A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |