SCHEMBL25320154

SCHEMBL25320154

CC(C)(C)OC(=O)N1CCc2sc3cc(OCc4ccccc4)ccc3c2CC1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
YAP1 P46937 3/20 0.47
GCK P35557 1/20 0.44
P2RX3 P56373 1/20 0.44
GPR119 Q8TDV5 2/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
GHSR Q92847 5/20 0.42
PRMT5 O14744 2/20 0.42
KIT P10721 1/20 0.41
FLT3 P36888 1/20 0.41
TLR9 Q9NR96 2/20 0.41
TLR7 Q9NYK1 1/20 0.41
MCHR1 Q99705 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30440168 1.00 YAP1 (0.47) YAP1GCKP2RX3GPR119CA12
SCHEMBL15781331 0.88 MCHR1 (0.55) MCHR1
SCHEMBL30439870 0.84 KDM4E (0.53) P2RX3GPR119
SCHEMBL25318904 0.84 KDM4E (0.53) P2RX3GPR119
SCHEMBL15781401 0.83 MCHR1 (0.53) MCHR1
SCHEMBL15781315 0.82 MCHR1 (0.54) P2RX3MCHR1
SCHEMBL25319573 0.82 KDM4E (0.44) P2RX3CA12CA1CA2
SCHEMBL30439980 0.82 KDM4E (0.44) P2RX3CA12CA1CA2
SCHEMBL25895766 0.82 HRH3 (0.58) MCHR1
SCHEMBL31354957 0.82 HRH3 (0.58) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051346-A1 BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2025-02-13 US disclosed
WO-2023114858-A1 BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed
WO-2023114858-A1 BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051346-A1 BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF GAP43, BDNF, DBH YAP1 2053/4885GCK 3224/4885P2RX3 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.