SCHEMBL2532023

SCHEMBL2532023

CC(=O)Nc1c(C)c(C(=O)c2conc2Br)nc(C(=O)O)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490452 0.82 TDP1 (0.40)
SCHEMBL2531996 0.78 ALOX12 (0.32)
SCHEMBL3842843 0.71 TDP1 (0.43)
SCHEMBL3330390 0.67 ALDH1A1 (0.35)
SCHEMBL30722779 0.61 KDM4E (0.37)
SCHEMBL26988845 0.61 KDM4E (0.37)
SCHEMBL2493294 0.60 TDP1 (0.39)
SCHEMBL6164151 0.60 ALDH1A1 (0.43)
SCHEMBL27837967 0.58 CYP3A4 (0.36)
SCHEMBL15063403 0.57 KDM4E (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2939540-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2369929-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 EP disclosed
WO-2010060581-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO disclosed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP disclosed