SCHEMBL2532032

SCHEMBL2532032

COc1o[c]c(OCc2ccccn2)c1OC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SYK P43405 13/20 0.42
AURKB Q96GD4 3/20 0.42
INCENP Q9NQS7 3/20 0.42
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
ABCB1 P08183 2/20 0.38
HTR1A P08908 2/20 0.38
DRD2 P14416 2/20 0.38
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5759834 0.72 GABRA1 (0.41) SYKKDM4ESMN1; SMN2ALDH1A1ABCB1
SCHEMBL5757896 0.70 SYK (0.40) SYKAURKBINCENPKDM4ESMN1; SMN2
SCHEMBL17712565 0.69 SYK (0.58) SYKAURKBINCENPKDM4EL3MBTL1
SCHEMBL754866 0.68
SCHEMBL29424113 0.68
SCHEMBL1073540 0.67 SYK (0.68) SYKAURKBINCENPKDM4ESMN1; SMN2
SCHEMBL8576652 0.67
SCHEMBL5758441 0.67 SMN1; SMN2 (0.43) SYKAURKBINCENPKDM4ESMN1; SMN2
Ammonia Solution, Strong SCHEMBL27924600 0.66 SYK (0.49) SYKAURKBINCENPKDM4ESMN1; SMN2
SCHEMBL15475121 0.66 SYK (0.53) SYKAURKBINCENPKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014207100-A1 A PROCESS FOR COATING PAPER WITH CELLULOSE USING A SOLUTION CONTAINING CELLULOSE BASF SE (DE) 2014-12-31 WO disclosed
US-20110253929-A1 MIXTURES OF HYDROPHOBIC AND HYDROPHILIC IONIC LIQUIDS AND USE THEREOF IN LIQUID RING COMPRESSORS BASF SE (DE) 2011-10-20 US disclosed