Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 15/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898067 | 0.83 | GRM2 (0.47) | GRM2GLO1 | |
| SCHEMBL25898581 | 0.80 | GRM2 (0.44) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25322286 | 0.80 | TIPARP (0.53) | — | |
| SCHEMBL25322280 | 0.80 | TIPARP (0.53) | — | |
| SCHEMBL26658705 | 0.80 | TIPARP (0.53) | — | |
| SCHEMBL25898051 | 0.79 | KDM4E (0.44) | GRM2KDM4EHTTGLO1 | |
| SCHEMBL25898732 | 0.77 | GRM2 (0.51) | GRM2 | |
| SCHEMBL25897776 | 0.76 | GRM2 (0.46) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25320933 | 0.74 | GRM2 (0.35) | GRM2 | |
| SCHEMBL25320929 | 0.74 | GRM2 (0.35) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |