Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL152565 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL29445334 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL29893012 | 0.78 | MAPT (0.48) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL8701501 | 0.78 | MAPT (0.48) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL28044599 | 0.77 | TDP1 (0.53) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL30159356 | 0.77 | BACE1 (0.51) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL2329389 | 0.77 | KMT2A (0.50) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL25322076 | 0.77 | BACE1 (0.51) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL25370522 | 0.77 | KDM4E (0.36) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL25322621 | 0.77 | BACE1 (0.42) | HPGDBACE1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |