Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893012 | 0.78 | MAPT (0.48) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL8701501 | 0.78 | MAPT (0.48) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL25322113 | 0.77 | ALDH1A1 (0.46) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL30159356 | 0.77 | BACE1 (0.51) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL25322076 | 0.77 | BACE1 (0.51) | ALDH1A1HPGDMAPTGLAACHE | |
| SCHEMBL2329389 | 0.77 | KMT2A (0.50) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL22017128 | 0.74 | GAA (0.44) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL28035883 | 0.74 | TDP1 (0.59) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL30106733 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1HPGDMAPTGLA | |
| SCHEMBL28842468 | 0.73 | ALDH1A1 (0.46) | TDP1ALDH1A1HPGDMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157297-A | PRMT5 inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-102365277-B | JUN N-terminal kinase inhibitors | ELAN PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |