Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322662 | 1.00 | IRAK4 (0.32) | IRAK4LPLLIPGUSP30 | |
| SCHEMBL25958846 | 0.86 | LPL (0.34) | IRAK4LPLLIPG | |
| SCHEMBL25334200 | 0.86 | LPL (0.34) | IRAK4LPLLIPG | |
| SCHEMBL25334207 | 0.86 | LPL (0.34) | IRAK4LPLLIPG | |
| SCHEMBL29081357 | 0.84 | TLR8 (0.36) | IRAK4LPLLIPG | |
| SCHEMBL22041263 | 0.80 | LPL (0.39) | IRAK4LPLLIPG | |
| SCHEMBL30514914 | 0.78 | IRAK4 (0.33) | IRAK4LPLLIPG | |
| SCHEMBL25958976 | 0.78 | IRAK4 (0.33) | IRAK4LPLLIPG | |
| SCHEMBL25323831 | 0.78 | HRH3 (0.38) | — | |
| SCHEMBL25322012 | 0.78 | HRH3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | RB1, CYP1B1, REN | IRAK4 4158/4885LPL 3972/4885LIPG 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.