Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322323 | 0.85 | MAPT (0.37) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21801802 | 0.83 | IRAK4 (0.42) | IRAK4IDO1TDO2LPLLIPG | |
| SCHEMBL25323249 | 0.83 | MAPT (0.35) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1237710 | 0.82 | ALDH1A1 (0.41) | MAPTKMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL17113535 | 0.76 | IRAK4 (0.39) | IRAK4IDO1TDO2LPLLIPG | |
| SCHEMBL25428650 | 0.76 | ERN1 (0.41) | MAPTKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL2933541 | 0.75 | ALDH1A1 (0.41) | MAPTKMT2AALDH1A1KDM4ECYP3A4 | |
| Acetic Acid SCHEMBL25322175 | 0.73 | IDO1 (0.35) | IRAK4IDO1TDO2LPLLIPG | |
| SCHEMBL24873712 | 0.73 | LPL (0.40) | IRAK4IDO1TDO2LPLLIPG | |
| Acetic Acid SCHEMBL25322169 | 0.72 | IDO1 (0.37) | IRAK4IDO1TDO2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |