Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550980 | 0.91 | IDH1 (0.41) | CYP11B2GRIN2BIDH1PARP10PARP11 | |
| SCHEMBL25322415 | 0.91 | IDH1 (0.41) | CYP11B2GRIN2BIDH1PARP10PARP11 | |
| SCHEMBL25322417 | 0.91 | IDH1 (0.41) | CYP11B2GRIN2BIDH1PARP10PARP11 | |
| Trifluoroacetic Acid SCHEMBL25323426 | 0.84 | SLC22A12 (0.39) | CYP11B2DYRK1ACYP11B1 | |
| Trifluoroacetic Acid SCHEMBL25324225 | 0.76 | NPC1 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL25322362 | 0.76 | EGFR (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL25322512 | 0.75 | CHRNB4 (0.44) | GRIN2B | |
| SCHEMBL25323877 | 0.74 | NOS3 (0.37) | CYP11B2PARP10PARP11CYP11B1 | |
| SCHEMBL25323875 | 0.74 | NOS3 (0.37) | CYP11B2PARP10PARP11CYP11B1 | |
| SCHEMBL30551484 | 0.74 | NOS3 (0.37) | CYP11B2PARP10PARP11CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |