SCHEMBL25323073

SCHEMBL25323073

CCn1cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2n1.CCn1cc2ccc(C3=CCC(C)CN3C(=O)O)cc2n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 2/20 0.32
▸ LPL P06858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25323067 1.00 LIPG (0.32) LIPGLPL
SCHEMBL25322677 0.92 LIPG (0.32) LIPGLPL
SCHEMBL25322673 0.92 LIPG (0.32) LIPGLPL
SCHEMBL25325056 0.88 NOTUM (0.36) —
SCHEMBL25325052 0.88 NOTUM (0.36) —
SCHEMBL25322876 0.87 LPL (0.32) LIPGLPL
SCHEMBL25321630 0.87 TYK2 (0.34) LIPGLPL
SCHEMBL25321628 0.87 TYK2 (0.34) LIPGLPL
SCHEMBL25322873 0.87 LPL (0.32) LIPGLPL
SCHEMBL25321900 0.79 IRAK4 (0.32) LIPGLPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146990-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 — — WO disclosed
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