Phenazopyridine

Phenazopyridine

SCHEMBL253232

Nc1ccc(/N=N/c2ccccc2)c(N)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Phenazopyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 1.00
KMT2A Q03164 8/20 1.00
MAPK1 P28482 6/20 1.00
TDP1 Q9NUW8 5/20 1.00
CYP3A4 P08684 3/20 1.00
LMNA P02545 3/20 1.00
HBB P68871 2/20 1.00
CYP1A2 P05177 2/20 1.00
HIF1A Q16665 2/20 1.00
USP2 O75604 1/20 1.00
CHRM1 P11229 1/20 1.00
CYP2C9 P11712 1/20 1.00
DRD2 P14416 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
CHRM3 P20309 1/20 1.00
DRD1 P21728 1/20 1.00
TBXA2R P21731 1/20 1.00
PTGS1 P23219 1/20 1.00
SLC6A2 P23975 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazopyridine SCHEMBL360809 1.00 MEN1 (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL14340038 1.00 MEN1 (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL27863926 0.98 MEN1 (0.96) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL26499 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL215655 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL29392321 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL19357 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL14687482 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL28796595 0.98 MAPT (1.00) MEN1KMT2AMAPK1TDP1CYP3A4
Phenazopyridine SCHEMBL301672 0.96 MAPT (0.96) MEN1KMT2AMAPK1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5185 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
EP-4680203-A1 COMPOSITIONS FOR SUSTAINED RELEASE OF POORLY SOLUBLE ACTIVE INGREDIENTS Prolevi Bio AB (SE) 2026-01-21 EP claimed
EP-3699174-B1 COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME ILAB (KR) 2025-11-12 EP claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
US-12448559-B1 Puddle job with delayed setting of resin via a polymerization reaction with an activator HALLIBURTON ENERGY SERVICES, INC. (US) 2025-10-21 US claimed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
EP-4587062-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA Cellis AG (CH) 2025-07-23 EP claimed
US-20250205278-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING ABBOTT NICHOLAS L (US) 2025-06-26 US claimed
WO-2025111413-A1 TREATMENT FOR SKIN DISORDERS Mycotechnology, Inc. (US) 2025-05-30 WO claimed
CN-113227752-B Enhanced, rapid, homogeneous cell staining and assay 上海宜晟生物科技有限公司 2025-04-29 CN claimed
EP-0735861-A1 TISSUE MOISTURIZING AND ANTIMICROBIAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-10-09 EP claimed
EP-0110955-B1 BRAIN-SPECIFIC DRUG DELIVERY UNIV FLORIDA (US) 1995-08-23 EP claimed
WO-1995017175-A1 ANTIMICROBIAL WIPE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-06-29 WO claimed
WO-1995017165-A2 TISSUE MOISTURIZING AND ANTIMICROBIAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-06-29 WO claimed
EP-0599188-A1 Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity LIFEGROUP S.p.A. (IT) 1994-06-01 EP claimed
EP-0312132-B1 VETERINARY AND HUMAN MEDICAL REMEDY HAVING AN ANTIVIRAL AND ANTITUMOROUS ACTIVITY, CONTAINING 2,6-DIAMINO-3-PHENYL-AZO-PYRIDINE Hak, Barend Willem (NL) 1993-01-13 EP claimed
EP-0312132-A2 Veterinary and human medical remedy having an antiviral and antitumorous activity, containing 2,6-diamino-3-phenyl-azo-pyridine Hak, Barend Willem (NL) 1989-04-19 EP claimed
EP-0222425-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-20 EP claimed
EP-0218300-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-04-15 EP claimed
US-4393127-A Structure with a silicon body having through openings INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1983-07-12 US claimed