Phenazopyridine

Phenazopyridine

SCHEMBL301672

Br.Cl.Nc1ccc(/N=N/c2ccccc2)c(N)n1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Phenazopyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.96
MEN1 O00255 8/20 0.96
KMT2A Q03164 8/20 0.96
MAPK1 P28482 6/20 0.96
TDP1 Q9NUW8 5/20 0.96
CYP3A4 P08684 3/20 0.96
SMN1; SMN2 Q16637 3/20 0.96
HBB P68871 2/20 0.96
KDM4E B2RXH2 2/20 0.96
TSHR P16473 2/20 0.96
ALOX15 P16050 2/20 0.96
SARM1 Q6SZW1 1/20 0.96
HSD17B10 Q99714 1/20 0.96
LMNA P02545 3/20 0.93
CYP1A2 P05177 2/20 0.93
HIF1A Q16665 2/20 0.93
USP2 O75604 1/20 0.93
CHRM1 P11229 1/20 0.93
CYP2C9 P11712 1/20 0.93
DRD2 P14416 1/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazopyridine SCHEMBL453934 1.00 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL5973732 1.00 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL14687482 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL28796595 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL26499 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL215655 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL19357 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL29392321 0.98 MAPT (1.00) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL302506 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1
Phenazopyridine SCHEMBL6661856 0.96 MAPT (0.96) MAPTMEN1KMT2AMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412775-A2 SOLDER ADHESIVE AND A PRODUCTION METHOD FOR THE SAME, AND AN ELECTRONIC DEVICE COMPRISING THE SAME Duksan Hi-Metal Co., Ltd. (KR) 2012-02-01 EP claimed
US-6086738-A FORMING CHARACTERS AND IMAGES ON A CYLINDER AS A POSITIVE ELECTRODE WITH AN INK WHICH BRINGS ABOUT COLORED-COAGULATED COLLOID WITH ELECTRIC CHARGE, TRANSFERRING THE CHARACTERS AND IMAGES TO THE RECORD SHEET TOKUSHO PAPER MFG. CO. LTD. (JP) 2000-07-11 US claimed
EP-0776768-B1 Record sheet used in electrocoagulation printing method TOKUSHU PAPER MFG CO LTD (JP) 2000-03-01 EP claimed
EP-0776768-A2 Record sheet used in electrocoagulation printing method TOKUSHU PAPER MFG. CO., LTD (JP) 1997-06-04 EP claimed
US-20240199607-A1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY ASTEX THERAPEUTICS LIMITED (GB) 2024-06-20 US disclosed
US-11866428-B2 Bicyclic heterocycle compounds and their uses in therapy ASTEX THERAPEUTICS LIMITED (GB) 2024-01-09 US disclosed
EP-4292820-A1 INK SET FOR INKJET RECORDING, INKJET RECORDING METHOD, MAINTENANCE METHOD, AND INKJET RECORDING APPARATUS KONICA MINOLTA, INC. (JP) 2023-12-20 EP disclosed
EP-3363644-B1 RECORDING METHOD AND RECORDING APPARATUS SEIKO EPSON CORP (JP) 2023-05-03 EP disclosed
US-20210122749-A1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY ASTEX THERAPEUTICS LIMITED (GB) 2021-04-29 US disclosed
EP-3375828-B1 INK JET RECORDING METHOD AND INK SET SEIKO EPSON CORP (JP) 2021-02-24 EP disclosed
US-10907065-B2 Ink jet recording method and ink set SEIKO EPSON CORPORATION 2021-02-02 US disclosed
EP-2699562-B1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY ASTEX THERAPEUTICS LTD (GB) 2020-12-23 EP disclosed
US-4518774-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-05-21 US disclosed
US-4500461-A Cyanohydrin process THE UPJOHN COMPANY (US) 1985-02-19 US disclosed
US-4379922-A CHEMICAL INTERMEDIATES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-04-12 US disclosed
EP-0048504-A2 Intermediate compounds for preparing cephem compounds; processes for their preparation and processes for preparing cephem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-03-31 EP disclosed
US-4298529-A INTERMEDIATES FOR USEFUL CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-11-03 US disclosed
EP-0009671-A2 Starting compounds for preparing cephem compounds and processes for their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-16 EP disclosed
US-4103082-A ANTIMICROBIAL SUAMI T 1978-07-25 US disclosed
US-4057561-A OVULATION INHIBITOR, ANDROGENIC, ANABOLIC HOFFMANN-LA ROCHE INC. (US) 1977-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199607-A1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 MAPT 301/4885MEN1 457/4885KMT2A 2579/4885
US-20210122749-A1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 MAPT 301/4885MEN1 457/4885KMT2A 2579/4885
US-11866428-B2 Bicyclic heterocycle compounds and their uses in therapy H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 MAPT 301/4885MEN1 457/4885KMT2A 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.