Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097541 | 1.00 | CNR2 (0.49) | CNR2CNR1TRPV3ALDH1A1LMNA | |
| SCHEMBL27202748 | 0.88 | CNR2 (0.47) | CNR2CNR1LMNAGPR119JAK2 | |
| SCHEMBL30849193 | 0.88 | CNR2 (0.49) | CNR2CNR1TRPV3ALDH1A1LMNA | |
| SCHEMBL29148539 | 0.88 | CNR2 (0.49) | CNR2CNR1TRPV3ALDH1A1LMNA | |
| SCHEMBL13132432 | 0.83 | GPR119 (0.50) | CNR2CNR1TRPV3GPR119KDM4E | |
| SCHEMBL21245809 | 0.82 | ALOX5AP (0.50) | CNR2CNR1TRPV3GPR119KDM4E | |
| SCHEMBL29790202 | 0.81 | BACE1 (0.53) | MAPTKMT2A | |
| SCHEMBL22912768 | 0.81 | BACE1 (0.53) | MAPTKMT2A | |
| SCHEMBL31487235 | 0.79 | GPR119 (0.45) | TRPV3GPR119 | |
| SCHEMBL30849217 | 0.79 | USP30 (0.48) | ALDH1A1GPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171418-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2025-05-29 | — | — | US | disclosed |
| EP-4460497-A1 | PARP1 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| CN-117447449-A | PARP1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023146960-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146960-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171418-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP12 | CNR2 4033/4885CNR1 3765/4885TRPV3 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.