Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29148533 | 1.00 | USP30 (0.48) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL29148532 | 1.00 | USP30 (0.48) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL29148491 | 0.90 | USP30 (0.49) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL30849213 | 0.89 | ALDH1A1 (0.47) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL31487235 | 0.82 | GPR119 (0.45) | USP30GPR119PIK3CD | |
| SCHEMBL31048018 | 0.80 | PIM1 (0.41) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL31048004 | 0.80 | PIM1 (0.41) | USP30HDAC4HDAC6BTKALDH1A1 | |
| SCHEMBL31686010 | 0.80 | USP30 (0.58) | USP30BTKALDH1A1PARP1NPC1 | |
| SCHEMBL25324271 | 0.79 | CNR2 (0.49) | ALDH1A1MAPTGPR119 | |
| SCHEMBL31097541 | 0.79 | CNR2 (0.49) | ALDH1A1MAPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447449-A | PARP1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |