SCHEMBL2532466

SCHEMBL2532466

C=CCO[C@@H]1O[C@H](COS(=O)(=O)c2ccc(C)cc2)[C@@H](OC(=O)CCNC(=O)OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SELP P16109 3/20 0.36
▸ LMNA P02545 1/20 0.36
▸ FGF1 P05230 5/20 0.35
▸ FGF2 P09038 3/20 0.35
▸ VEGFA P15692 3/20 0.35
▸ HPSE Q9Y251 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ TGM2 P21980 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CA1 P00915 2/20 0.34
▸ CA2 P00918 2/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ P2RX7 Q99572 1/20 0.34
▸ NT5E P21589 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ TACR1 P25103 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3398993 1.00 SELP (0.36) SELPLMNAFGF1FGF2VEGFA
SCHEMBL13224918 1.00 SELP (0.36) SELPLMNAFGF1FGF2VEGFA
SCHEMBL2530520 1.00 SELP (0.36) SELPLMNAFGF1FGF2VEGFA
SCHEMBL13248405 0.94 SELP (0.37) SELPLMNAFGF1FGF2VEGFA
SCHEMBL2175355 0.84 FGF1 (0.44) SELPFGF1FGF2VEGFAHPSE
SCHEMBL6929305 0.84 FGF1 (0.44) SELPFGF1FGF2VEGFAHPSE
SCHEMBL6923504 0.84 FGF1 (0.44) SELPFGF1FGF2VEGFAHPSE
SCHEMBL13057268 0.84 FGF1 (0.44) SELPFGF1FGF2VEGFAHPSE
SCHEMBL13224912 0.81 TGM2 (0.38) LMNAGAATGM2MEN1KMT2A
SCHEMBL13224917 0.81 FGF1 (0.40) SELPLMNAFGF1FGF2VEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2388264-A1 COMPOUND RETAINED IN TUMOR Toyo Suisan Kaisha, Ltd. (JP) 2011-11-23 — — EP disclosed
US-20110254443-A1 PHASE AND FREQUENCY LOCKED MAGNETRON MUONS, INC. 2011-10-20 — — US disclosed
US-20100202971-A1 COMPOUND HAVING TUMOR-RESIDENT PROPERTY OHTA KEISUKE 2010-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100202971-A1 COMPOUND HAVING TUMOR-RESIDENT PROPERTY HRH3, HRH4, HNRNPH3 SELP 3654/4885LMNA 3710/4885FGF1 3729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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