Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536161 | 0.89 | GRM5 (0.42) | GRM5SPREPHX2ALDH1A1MEN1 | |
| SCHEMBL25326735 | 0.83 | USP30 (0.47) | GRM5GPR183CYP3A4MEN1KMT2A | |
| SCHEMBL29772893 | 0.81 | CYP11B2 (0.50) | GRM5GPR183CYP3A4MEN1KMT2A | |
| SCHEMBL24628132 | 0.81 | CYP11B2 (0.50) | GRM5GPR183CYP3A4MEN1KMT2A | |
| SCHEMBL1394929 | 0.79 | SCD (0.47) | FFAR4GPR183CYP3A4HIF1AUSP2 | |
| SCHEMBL30700043 | 0.78 | MAPT (0.41) | FFAR4GRM5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30553399 | 0.77 | SLC6A2 (0.40) | FFAR4GRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL25943495 | 0.77 | SLC6A2 (0.40) | FFAR4GRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL29772849 | 0.77 | CYP11B2 (0.48) | GRM5GPR183CYP3A4MEN1KMT2A | |
| SCHEMBL24628355 | 0.77 | CYP11B2 (0.48) | GRM5GPR183CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |