Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30553245 | 1.00 | MGLL (0.41) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL25325011 | 1.00 | MGLL (0.41) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL30553212 | 1.00 | MGLL (0.41) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL25324972 | 1.00 | MGLL (0.41) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL30553168 | 0.95 | MGLL (0.40) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL25325478 | 0.95 | MGLL (0.40) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL30553283 | 0.94 | MGLL (0.45) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL25325009 | 0.94 | MGLL (0.45) | MGLLCCNE1CDK2CNR2GSK3B | |
| SCHEMBL25325955 | 0.88 | MGLL (0.40) | MGLL | |
| SCHEMBL30553282 | 0.88 | MGLL (0.40) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-27 | — | — | US | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250099448-A1 | HETEROCYCLIC COMPOUNDS | OPRM1, CYP1A1, CYP3A4 | MGLL 3523/4885CCNE1 642/4885CDK2 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.