Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 7/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.59 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.59 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.59 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.59 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.59 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.59 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749369 | 0.82 | DYRK1A (0.54) | PARP2DYRK1AKDM4ERAB9AKMT2A | |
| SCHEMBL25918359 | 0.77 | PARP10 (0.69) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL11536264 | 0.76 | PARP10 (0.73) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL25323961 | 0.75 | PARP10 (1.00) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL25325088 | 0.73 | PARP2 (1.00) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL25324408 | 0.71 | PARP2 (1.00) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL19718859 | 0.71 | PARP10 (0.66) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL15245382 | 0.70 | PARP2 (0.64) | PARP2PARP10PARP15TNKS2PARP14 | |
| SCHEMBL130860 | 0.67 | KDM4E (0.57) | DYRK1AKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL18747058 | 0.67 | PARP10 (0.51) | PARP2PARP10PARP15TNKS2PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2025-06-05 | — | — | US | disclosed |
| EP-4469046-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | Oulun Yliopisto (FI) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144450-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | OULUN YLIOPISTO (FI) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177359-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS | NAMPT, NADK, NQO1 | PARP2 15/4885PARP10 11/4885PARP15 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.