SCHEMBL25918359

SCHEMBL25918359

Cc1ccc2c(c1)sc1nnc(O)n12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 8/20 0.69
PARP2 Q9UGN5 8/20 0.69
PARP15 Q460N3 6/20 0.69
TNKS2 Q9H2K2 5/20 0.69
PARP14 Q460N5 3/20 0.69
TNKS O95271 2/20 0.69
PARP1 P09874 2/20 0.69
PARP11 Q9NR21 2/20 0.69
PARP4 Q9UKK3 2/20 0.69
PARP3 Q9Y6F1 2/20 0.69
TIPARP Q7Z3E1 1/20 0.69
PARP16 Q8N5Y8 1/20 0.69
PARP12 Q9H0J9 1/20 0.69
RAB9A P51151 4/20 0.45
NPC1 O15118 3/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.43
MAPT P10636 3/20 0.41
MEN1 O00255 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11536264 0.83 PARP10 (0.73) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL25323961 0.82 PARP10 (1.00) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL19718859 0.78 PARP10 (0.66) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL25324408 0.78 PARP2 (1.00) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL15245382 0.77 PARP2 (0.64) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL25325548 0.77 PARP2 (0.59) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL11741753 0.76 CHEK1 (0.66) PARP2TNKS2RAB9ANPC1KMT2A
SCHEMBL11534080 0.70 PARP2 (0.55) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL7331138 0.70 PARP10 (0.51) PARP10PARP2PARP15TNKS2PARP14
SCHEMBL18747058 0.70 PARP10 (0.51) PARP10PARP2PARP15TNKS2PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023144450-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS OULUN YLIOPISTO (FI) 2023-08-03 WO disclosed