Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551630 | 0.88 | MAOB (0.45) | HPGDMAPK1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL25324335 | 0.88 | MAOB (0.45) | HPGDMAPK1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31578447 | 0.88 | MAOB (0.45) | HPGDMAPK1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL25324339 | 0.88 | MAOB (0.45) | HPGDMAPK1KDM4EHSD17B10ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL25322512 | 0.85 | CHRNB4 (0.44) | PIN1KDM4ESMN1; SMN2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL25323426 | 0.84 | SLC22A12 (0.39) | CYP1A2CYP3A4CYP2C19CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL25322362 | 0.79 | EGFR (0.38) | LMNAHTTHPGDMAPK1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL25324225 | 0.77 | NPC1 (0.39) | LMNACYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL25321892 | 0.74 | HTR1A (0.44) | MEN1KMT2A | |
| SCHEMBL25321886 | 0.74 | HTR1A (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |