Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 15/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30886178 | 0.85 | GRM5 (0.37) | GRM5GRM1HTR2B | |
| SCHEMBL30886968 | 0.85 | GRM5 (0.37) | GRM5GRM1HTR2B | |
| SCHEMBL25914460 | 0.85 | GRM5 (0.37) | GRM5GRM1HTR2B | |
| SCHEMBL25319331 | 0.83 | TLR8 (0.39) | — | |
| Bicarbonate SCHEMBL25323696 | 0.82 | HDAC8 (0.33) | — | |
| SCHEMBL25322655 | 0.82 | TLR8 (0.37) | — | |
| SCHEMBL25323112 | 0.80 | NPC1 (0.44) | KDM4E | |
| SCHEMBL25322039 | 0.79 | NPC1 (0.40) | KDM4E | |
| SCHEMBL30886216 | 0.78 | MAPT (0.40) | KDM4E | |
| SCHEMBL25325052 | 0.77 | NOTUM (0.36) | SCD5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |