Demannose

Demannose

SCHEMBL25326591

CCc1ccccc1C(=O)O.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 2/20 0.40
FOLH1 Q04609 2/20 0.39
TSHR P16473 1/20 0.36
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.34
PTPN1 P18031 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC16A3 O15427 1/20 0.34
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
PDE4A P27815 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL23567081 0.89 ALDH1A1 (0.45) ALDH1A1ALOX15KDM4EKMT2APDE4A
Phthalic Acid SCHEMBL30930043 0.89 ALDH1A1 (0.45) ALDH1A1ALOX15KDM4EKMT2APDE4A
Demannose SCHEMBL27692132 0.82 MAPT (0.40) TSHRALDH1A1ALOX15TDP1POLB
Phthalic Acid SCHEMBL9109455 0.82 HSD17B10 (0.47) TSHRALDH1A1ALOX15TDP1POLB
Demannose SCHEMBL11356881 0.80 TSHR (0.45) TSHRALDH1A1TDP1TP53PDE4A
Demannose SCHEMBL27769187 0.80 TSHR (0.45) TSHRALDH1A1TDP1TP53PDE4A
Aspirin SCHEMBL2174051 0.80 KDM4E (0.58) TSHRALDH1A1TDP1CYP2C9HTT
Diethyl Phthalate SCHEMBL28152327 0.78 TSHR (0.57) TSHRALDH1A1TDP1KDM4ETP53
Demannose SCHEMBL28870326 0.78 LMNA (0.37) TSHRALDH1A1TDP1KDM4EMEN1
Anthranilic Acid SCHEMBL27914571 0.78 MAPT (0.41) TSHRALDH1A1ALOX15TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141693-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 WO disclosed
WO-2023141692-A1 SYNTHETIC GLYCOLIPIDS AND GLYCOLIPOSOME COMPOSITIONS SUITABLE FOR CARGO DELIVERY TO THE CENTRAL NERVOUS SYSTEM KORANEX CAPITAL (CA) 2023-08-03 WO disclosed