Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912457 | 1.00 | LMNA (0.59) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL12992111 | 1.00 | LMNA (0.59) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25322998 | 1.00 | LMNA (0.59) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25323572 | 1.00 | LMNA (0.59) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25912307 | 1.00 | LMNA (0.59) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7296344 | 0.84 | CYP19A1 (0.43) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL7297224 | 0.84 | CYP19A1 (0.43) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL4340293 | 0.84 | CYP19A1 (0.43) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25189601 | 0.84 | GRIN1 (0.65) | LMNACYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3118670 | 0.84 | GRIN1 (0.65) | LMNACYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137529-A1 | ANTI-PARASITE COMPOUNDS | AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2023-07-27 | — | — | WO | disclosed |