Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21831016 | 1.00 | MAPK14 (0.37) | MAPK14ALDH1A1DPP8CACNA1BKIT | |
| SCHEMBL21831810 | 0.86 | MAPK14 (0.37) | MAPK14DPP8CACNA1BKITDPP4 | |
| SCHEMBL25328216 | 0.86 | MAPK14 (0.37) | MAPK14DPP8CACNA1BKITDPP4 | |
| SCHEMBL21910374 | 0.85 | TACR1 (0.37) | MAPK14ALDH1A1HDAC1HDAC2 | |
| SCHEMBL30554486 | 0.85 | TACR1 (0.37) | MAPK14ALDH1A1HDAC1HDAC2 | |
| SCHEMBL21831526 | 0.84 | ALDH1A1 (0.38) | MAPK14ALDH1A1DPP4DPP7 | |
| SCHEMBL23579491 | 0.84 | CYP2D6 (0.35) | MAPK14DPP8CACNA1BDPP4DPP7 | |
| SCHEMBL25327588 | 0.83 | L3MBTL1 (0.36) | MAPK14ALDH1A1 | |
| SCHEMBL21831643 | 0.83 | L3MBTL1 (0.36) | MAPK14ALDH1A1 | |
| SCHEMBL21831647 | 0.82 | MAPK14 (0.35) | MAPK14ALDH1A1DPP8CACNA1BKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814348-B9 | SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-3814348-B1 | SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |