Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233717 | 0.84 | LMNA (0.69) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL17384714 | 0.82 | LMNA (0.54) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL14236720 | 0.81 | LMNA (0.49) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL17080008 | 0.79 | LMNA (0.50) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL4809458 | 0.79 | LMNA (0.58) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL12051770 | 0.79 | PKM (0.60) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL7806456 | 0.78 | BRD9 (0.53) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL25669208 | 0.77 | BRD9 (0.49) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL848403 | 0.77 | LMNA (0.56) | LMNAPKMMAPK1TP53SMN1; SMN2 | |
| SCHEMBL294756 | 0.77 | LMNA (0.52) | LMNAPKMMAPK1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023145769-A1 | γ-LACTAM COMPOUND AND COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2023-08-03 | — | — | WO | disclosed |
| WO-2023145769-A1 | γ-LACTAM COMPOUND AND COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2023-08-03 | — | — | WO | disclosed |