Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21831371 | 1.00 | SLC6A9 (0.57) | SLC6A9MAPK14DGKADGKZOPRD1 | |
| SCHEMBL21831860 | 0.86 | MAPK14 (0.48) | SLC6A9MAPK14DGKADGKZOPRD1 | |
| SCHEMBL21831278 | 0.86 | MAPK14 (0.48) | SLC6A9MAPK14DGKADGKZOPRD1 | |
| SCHEMBL21831485 | 0.86 | MAPK14 (0.48) | SLC6A9MAPK14DGKADGKZOPRD1 | |
| SCHEMBL25328436 | 0.86 | MAPK14 (0.48) | SLC6A9MAPK14DGKADGKZOPRD1 | |
| SCHEMBL26925850 | 0.86 | SLC6A9 (0.42) | SLC6A9MAPK14OPRD1KDM4ECYP1A2 | |
| SCHEMBL26927722 | 0.85 | SLC6A9 (0.49) | SLC6A9DGKADGKZOPRD1KDM4E | |
| SCHEMBL21831477 | 0.83 | OPRD1 (0.41) | SLC6A9MAPK14OPRD1KDM4ECYP1A2 | |
| SCHEMBL30554408 | 0.82 | SLC6A9 (0.48) | SLC6A9MAPK14DGKADGKZ | |
| SCHEMBL26944522 | 0.82 | SLC6A9 (0.48) | SLC6A9MAPK14DGKADGKZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814348-B9 | SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-01 | — | — | EP | disclosed |
| EP-3814348-B1 | SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |