Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523211 | 0.97 | AKR1C3 (0.40) | AKR1C3AOC3ENPP3ENPP1ENPP2 | |
| SCHEMBL2529164 | 0.90 | PPARG (0.44) | ENPP3ENPP1ENPP2P2RX7EGFR | |
| SCHEMBL2531504 | 0.90 | EGFR (0.43) | AOC3ENPP3ENPP1ENPP2EGFR | |
| SCHEMBL2529241 | 0.90 | EGFR (0.40) | AOC3ENPP3ENPP1EGFRMEN1 | |
| SCHEMBL2528867 | 0.90 | AOC3 (0.45) | AOC3EGFRMEN1ALDH1A1MAPT | |
| SCHEMBL2526994 | 0.90 | P2RX7 (0.41) | P2RX7EGFRMEN1ALDH1A1MAPT | |
| SCHEMBL2527589 | 0.90 | ENPP3 (0.44) | ENPP3ENPP1ENPP2EGFRMEN1 | |
| SCHEMBL2526637 | 0.89 | P2RX7 (0.40) | AOC3ENPP3ENPP1ENPP2P2RX7 | |
| SCHEMBL2528584 | 0.89 | MEN1 (0.45) | AOC3ENPP3ENPP1ENPP2EGFR | |
| SCHEMBL2526875 | 0.89 | MEN1 (0.48) | AOC3ENPP3ENPP1ENPP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | AKR1C3 1105/4885AOC3 2105/4885ENPP3 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.