Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327354 | 0.88 | RIPK1 (0.58) | RIPK1PDK2PDK1PDK3PDK4 | |
| SCHEMBL25325663 | 0.86 | RIPK1 (0.39) | RIPK1PDK2PDK1PDK3PDK4 | |
| SCHEMBL25324187 | 0.85 | RIPK1 (0.40) | RIPK1KIF11 | |
| SCHEMBL30522896 | 0.85 | RIPK1 (0.40) | RIPK1KIF11 | |
| SCHEMBL25326625 | 0.85 | RIPK1 (0.40) | RIPK1KIF11 | |
| SCHEMBL25326627 | 0.85 | RIPK1 (0.40) | RIPK1KIF11 | |
| SCHEMBL25324182 | 0.85 | RIPK1 (0.40) | RIPK1KIF11 | |
| SCHEMBL25327591 | 0.84 | PDK2 (0.37) | RIPK1PDK2PDK1PDK3PDK4 | |
| SCHEMBL25326988 | 0.83 | RIPK1 (0.53) | RIPK1PDK2PDK1PDK3PDK4 | |
| SCHEMBL25326674 | 0.82 | KMT2A (0.41) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |