Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326910 | 0.89 | RIPK1 (0.44) | PDK2PDK1PDK3PDK4RIPK1 | |
| SCHEMBL25328951 | 0.84 | RIPK1 (0.45) | PDK2PDK1PDK3PDK4RIPK1 | |
| SCHEMBL25328193 | 0.84 | TACR1 (0.41) | NR1H2NR1H3 | |
| SCHEMBL25917992 | 0.84 | TACR1 (0.41) | NR1H2NR1H3 | |
| SCHEMBL25329324 | 0.83 | GAA (0.38) | PDK2NR1H2NR1H3 | |
| SCHEMBL25327620 | 0.82 | SLC9A1 (0.35) | SLC6A9 | |
| SCHEMBL25327282 | 0.81 | PDK1 (0.56) | PDK2PDK1PDK3PDK4SLC6A9 | |
| SCHEMBL25326276 | 0.81 | PDK1 (0.56) | PDK2PDK1PDK3PDK4SLC6A9 | |
| SCHEMBL25326674 | 0.79 | KMT2A (0.41) | RIPK1CCR1 | |
| SCHEMBL25328898 | 0.77 | SMN1; SMN2 (0.34) | RIPK1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |