Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775754 | 0.88 | GAA (0.35) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL30457518 | 0.87 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL625779 | 0.87 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL10377763 | 0.85 | MEN1 (0.34) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL11670707 | 0.84 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL11672805 | 0.84 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL30667161 | 0.83 | MEN1 (0.39) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL658696 | 0.83 | GAA (0.39) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL7627786 | 0.83 | MEN1 (0.39) | MEN1ALDH1A1KMT2AGAAPOLB | |
| SCHEMBL8916742 | 0.82 | GAA (0.36) | MEN1ALDH1A1KMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3644991-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2023-08-02 | — | — | EP | disclosed |