SCHEMBL30457518

SCHEMBL30457518

Cc1ccc(S(=O)(=O)O)c(CC(F)(F)Cc2cc(C)ccc2S(=O)(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 2/20 0.37
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
CASP6 P55212 1/20 0.37
ELAVL1 Q15717 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEP1B Q16820 2/20 0.34
PTGS2 P35354 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MYC P01106 1/20 0.33
PTGS1 P23219 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
MPL P40238 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL625779 0.90 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL11672805 0.87 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL25329308 0.87 MEN1 (0.35) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL11670707 0.87 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL775754 0.87 GAA (0.35) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL30667161 0.86 MEN1 (0.39) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL7627786 0.86 MEN1 (0.39) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL658696 0.86 GAA (0.39) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL8916742 0.84 GAA (0.36) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL10377763 0.84 MEN1 (0.34) ALDH1A1MEN1KMT2AGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025007873-A1 KAT6 INHIBITOR 上海齐鲁制药研究中心有限公司 2025-01-09 WO disclosed
WO-2024240062-A1 PYRIDINE-PYRROLO DERIVATIVE AND USE THEREOF IN DRUGS 广东东阳光药业股份有限公司 2024-11-28 WO disclosed
CN-116940552-A Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2023-10-24 CN disclosed
CN-116261572-A Metal-ligand complex, catalyst composition for preparing ethylene-based polymer comprising the same, and method for preparing ethylene-based polymer using the same 沙特基础工业爱思开NEXLENE私人有限公司 2023-06-13 CN disclosed