Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25329352 | 0.80 | TDP1 (0.46) | KMT2A | |
| SCHEMBL25328809 | 0.77 | KMT2A (0.38) | KMT2ACYP2C19RAB9A | |
| SCHEMBL25021979 | 0.73 | GBA1 (0.44) | L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30306871 | 0.71 | PTGER4 (0.39) | L3MBTL1 | |
| SCHEMBL14378864 | 0.67 | PAOX (0.46) | KMT2ARECQL | |
| SCHEMBL4760430 | 0.67 | BRD4 (0.33) | KMT2ARAB9A | |
| SCHEMBL28184077 | 0.67 | PAOX (0.46) | KMT2ARECQL | |
| SCHEMBL374144 | 0.67 | POLB (0.33) | L3MBTL1KMT2ARAB9A | |
| SCHEMBL974356 | 0.67 | POLB (0.33) | L3MBTL1KMT2ARAB9A | |
| SCHEMBL4760434 | 0.66 | KMT2A (0.38) | KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |