Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328809 | 0.82 | KMT2A (0.38) | MEN1KMT2A | |
| SCHEMBL25329353 | 0.80 | L3MBTL1 (0.32) | KMT2A | |
| SCHEMBL8294047 | 0.79 | TDP1 (0.48) | TDP1MAOAMAOBMAN2B1DRD2 | |
| SCHEMBL25361923 | 0.79 | DRD2 (0.50) | TDP1MAOAMAOBMAN2B1DRD2 | |
| SCHEMBL23034881 | 0.78 | TDP1 (0.49) | TDP1MAOAMAOBDRD2KMT2A | |
| SCHEMBL25362872 | 0.77 | DRD2 (0.48) | TDP1MAOAMAOBMAN2B1DRD2 | |
| SCHEMBL14295885 | 0.74 | KMT2A (0.54) | MEN1KMT2A | |
| SCHEMBL25030631 | 0.74 | TDP1 (0.50) | TDP1MAOAMAOBMAN2B1DRD2 | |
| SCHEMBL25022225 | 0.74 | L3MBTL1 (0.44) | DRD2KMT2ACA1CA2 | |
| SCHEMBL28969100 | 0.74 | L3MBTL1 (0.44) | DRD2KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |