Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25329352 | 0.82 | TDP1 (0.46) | KMT2AMEN1 | |
| SCHEMBL25329353 | 0.77 | L3MBTL1 (0.32) | KMT2ARAB9ACYP2C19 | |
| SCHEMBL25021979 | 0.77 | GBA1 (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL30306871 | 0.75 | PTGER4 (0.39) | — | |
| SCHEMBL4760430 | 0.73 | BRD4 (0.33) | KMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4339603 | 0.71 | BRD4 (0.33) | KMT2ANPC1RAB9A | |
| SCHEMBL974356 | 0.70 | POLB (0.33) | KMT2ANPC1RAB9A | |
| SCHEMBL374144 | 0.70 | POLB (0.33) | KMT2ANPC1RAB9A | |
| SCHEMBL893175 | 0.69 | MAPK1 (0.37) | — | |
| SCHEMBL5656878 | 0.69 | RAB9A (0.61) | KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |