SCHEMBL25329665

SCHEMBL25329665

Cn1c(=S)n(C)c(=O)n(-c2cc(N)c(Cl)cc2F)c1=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
BRD9 Q9H8M2 1/20 0.32
GAA P10253 1/20 0.31
GRM4 Q14833 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30523830 1.00 TP53 (0.32) TP53MAPTBRD9GAAGRM4
SCHEMBL6590926 0.84 BRD9 (0.32) BRD9GAA
SCHEMBL7248396 0.84 HSP90AA1 (0.33) MAPTBRD9GRM4
SCHEMBL25328529 0.82 BRD9 (0.32) BRD9GRM4
SCHEMBL10575657 0.80 TP53 (0.33) TP53MAPTBRD9
SCHEMBL29189541 0.80 GRM4 (0.31) BRD9GRM4
SCHEMBL23635745 0.80 BRD9 (0.31) BRD9
SCHEMBL25331129 0.79 TRPV4 (0.31) BRD9
SCHEMBL4067527 0.79 NOTUM (0.36) MAPT
SCHEMBL31468720 0.79 TSHR (0.34) MAPTBRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023144004-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-08-03 WO disclosed
WO-2023144004-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-08-03 WO disclosed