SCHEMBL7248396

SCHEMBL7248396

Cn1c(=S)n(C)c(=O)n(-c2cc(O)c(Cl)cc2F)c1=O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 3/20 0.33
GRM4 Q14833 2/20 0.33
BRD9 Q9H8M2 1/20 0.33
HSD17B10 Q99714 2/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 2/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25328529 0.84 BRD9 (0.32) GRM4BRD9
SCHEMBL30523830 0.84 TP53 (0.32) GRM4BRD9MAPT
SCHEMBL25329665 0.84 TP53 (0.32) GRM4BRD9MAPT
SCHEMBL4067527 0.83 NOTUM (0.36) HPGDTSHRMAPTMEN1POLB
SCHEMBL31468720 0.83 TSHR (0.34) BRD9HPGDTSHRMAPTPOLB
SCHEMBL29189541 0.81 GRM4 (0.31) GRM4BRD9
SCHEMBL23635745 0.81 BRD9 (0.31) BRD9
SCHEMBL10575883 0.81 HSP90AA1 (0.32) HSP90AA1GRM4BRD9MAPTKMT2A
SCHEMBL25331129 0.80 TRPV4 (0.31) BRD9
SCHEMBL7253181 0.80 GAA (0.37) HSD17B10HPGDTSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613398-A Tetra-substituted phenyl ether (thioether) compound containing alkoxy acetate substituent and application thereof 江西天宇化工有限公司 2025-03-14 CN disclosed
US-6602825-B1 Cyclization of an isocyanate with a thiourea and carbonic acid BASF AKTIENGESELLSCHAFT (DE) 2003-08-05 US disclosed