SCHEMBL25329795

SCHEMBL25329795

CC(C)(C)c1ccn(C2CCNC2=O)n1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18307737 0.75 SRC (0.46)
SCHEMBL17031859 0.73 TSHR (0.36) ALDH1A1
SCHEMBL12413742 0.73 MEN1 (0.40) ALDH1A1
SCHEMBL19498026 0.72 HSD11B1 (0.32)
SCHEMBL22842971 0.69 SIGMAR1 (0.37) ALDH1A1
SCHEMBL13179351 0.68 SIGMAR1 (0.39) KDM4EALDH1A1
SCHEMBL12179266 0.68 KDM4E (0.34) KDM4EALDH1A1LRRK2
SCHEMBL25911335 0.67 KMT2A (0.34)
SCHEMBL20899095 0.67 KDM4E (0.36) KDM4EALDH1A1LRRK2
SCHEMBL25911555 0.66 MCHR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023145769-A1 γ-LACTAM COMPOUND AND COMPOSITION CONTAINING SAME 住友化学株式会社 2023-08-03 WO disclosed