Sugi Predict

Sugi Predict / Compounds / SCHEMBL25329989

SCHEMBL25329989

SCHEMBL25329989

COc1cc(F)c(CCl)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 1/20 0.61
▸ ALDH1A1 P00352 2/20 0.43
▸ KDM1A O60341 1/20 0.40
▸ MAOA P21397 1/20 0.40
▸ MAOB P27338 1/20 0.40
▸ CYP1A1 P04798 2/20 0.38
▸ CYP1B1 Q16678 2/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ TRAP1 Q12931 2/20 0.37
▸ HSP90B1 P14625 1/20 0.37
▸ CPS1 P31327 2/20 0.36
▸ NQO2 P16083 1/20 0.34
▸ CYP3A4 P08684 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33
▸ GFER P55789 1/20 0.33
▸ MEP1B Q16820 1/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA1 P00915 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13073165 0.79 TAAR1 (0.63) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL12509348 0.78 TAAR1 (0.57) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL855100 0.77 TAAR1 (0.73) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL3776543 0.77 TAAR1 (0.61) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL160725 0.77 TAAR1 (0.61) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL4573222 0.77 TAAR1 (0.61) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL13548269 0.76 TAAR1 (0.70) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL20562959 0.76 TAAR1 (1.00) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL16693753 0.75 TAAR1 (0.53) TAAR1ALDH1A1KDM1AMAOAMAOB
SCHEMBL4524516 0.74 ALDH1A1 (0.46) TAAR1ALDH1A1CYP1A1CYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250099494-A1 PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF HAIHE BIOPHARMA CO., LTD. (CN) 2025-03-27 — — US disclosed
EP-4467552-A1 PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF Haihe Biopharma Co., Ltd. (CN) 2024-11-27 — — EP disclosed
CN-118339172-A Phosphonic acid compounds and prodrugs thereof, preparation method and application thereof 上海海和药物研究开发股份有限公司 2024-07-12 — — CN disclosed
WO-2023138637-A1 PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF 上海海和药物研究开发股份有限公司 2023-07-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099494-A1 PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF, AND PREPARATION METHODS FOR AND USES OF PHOSPHONIC ACID COMPOUND AND PRODRUG THEREOF ENPP1, ENPP3, PPA1 TAAR1 3629/4885ALDH1A1 1602/4885KDM1A 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.