Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26352661 | 0.84 | TGFBR1 (0.42) | RAB9AMEN1KMT2AGRM5IRAK4 | |
| SCHEMBL29425317 | 0.84 | TGFBR1 (0.42) | RAB9AMEN1KMT2AGRM5IRAK4 | |
| SCHEMBL25336337 | 0.80 | KDM4E (0.52) | RAB9AKDM4EMEN1KMT2AIRAK4 | |
| SCHEMBL2011053 | 0.79 | MAPT (0.50) | RAB9AKDM4ENPC1IRAK4 | |
| SCHEMBL2009561 | 0.75 | TGFBR1 (0.51) | IRAK4 | |
| SCHEMBL29014091 | 0.73 | IRAK4 (0.40) | KDM4EMEN1KMT2AIRAK4 | |
| SCHEMBL25336136 | 0.72 | TGFBR1 (0.45) | — | |
| SCHEMBL25335649 | 0.72 | CYP1A2 (0.50) | MEN1KMT2A | |
| SCHEMBL26352686 | 0.72 | TGFBR1 (0.42) | RAB9ARIPK1MEN1KMT2AIRAK4 | |
| SCHEMBL25336656 | 0.72 | IRAK4 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4219453-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, CYP4F11, WEE1 | RAB9A 3016/4885RIPK1 2827/4885KDM4E 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.