Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011053 | 0.77 | MAPT (0.50) | IRAK4KDM4ERECQLMAPT | |
| SCHEMBL25336337 | 0.75 | KDM4E (0.52) | IRAK4MEN1KMT2AKDM4ERECQL | |
| SCHEMBL29014101 | 0.73 | TGFBR1 (0.43) | IRAK4 | |
| SCHEMBL27792151 | 0.73 | PARP1 (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL29014094 | 0.73 | TGFBR1 (0.41) | IRAK4 | |
| SCHEMBL25333352 | 0.73 | RAB9A (0.43) | IRAK4MEN1KMT2AKDM4E | |
| SCHEMBL25335649 | 0.73 | CYP1A2 (0.50) | MEN1KMT2AMAPT | |
| SCHEMBL2009561 | 0.71 | TGFBR1 (0.51) | IRAK4RECQLMAPT | |
| SCHEMBL29425317 | 0.69 | TGFBR1 (0.42) | IRAK4MEN1KMT2A | |
| SCHEMBL26352661 | 0.69 | TGFBR1 (0.42) | IRAK4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249692-A | Pyrazole compound as well as preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-06-09 | — | — | CN | disclosed |