Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17336955 | 0.86 | ALDH1A1 (0.45) | EGLN1NPC1MEN1KMT2AKDM4E | |
| SCHEMBL10662617 | 0.83 | TYR (0.53) | CYP3A4NPC1CYP1A2CYP2D6MEN1 | |
| SCHEMBL25332319 | 0.82 | LMNA (0.62) | TSHRMEN1KMT2AKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL10667322 | 0.82 | TYR (0.52) | CYP3A4NPC1CYP1A2CYP2D6MEN1 | |
| SCHEMBL17513534 | 0.81 | EGLN1 (0.53) | EGLN1CDC7CYP3A4CYP2C9NPSR1 | |
| SCHEMBL17336919 | 0.81 | NOTUM (0.58) | EGLN1MEN1KMT2A | |
| SCHEMBL14584212 | 0.79 | MEN1 (0.50) | CYP3A4CYP2C9NPSR1NPC1CYP1A2 | |
| SCHEMBL25332764 | 0.79 | FLT1 (0.51) | EGLN1 | |
| SCHEMBL10660863 | 0.78 | TYR (0.54) | — | |
| SCHEMBL25333961 | 0.77 | EGLN1 (0.51) | EGLN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129031-A1 | 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD (IN) | 2025-04-24 | — | — | US | disclosed |
| EP-4469442-A1 | 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF | PI Industries Ltd. (IN) | 2024-12-04 | — | — | EP | disclosed |
| CN-118696033-A | 1,2, 3-Triazole carbonyl sulfonamide compound and application thereof | PI工业有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2023144711-A1 | 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129031-A1 | 1,2,3-TRIAZOLE CARBONYL SULFONYLAMIDE COMPOUNDS AND USE THEREOF | GLP1R, CBR3, CBR1 | EGLN1 23/4885CDC7 4108/4885CYP3A4 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.