Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333528 | 1.00 | CTSK (0.40) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL14975127 | 0.85 | CTSK (0.44) | CTSKCTSLCTSBCTSH | |
| SCHEMBL6402771 | 0.77 | CTSK (0.44) | CTSKCTSLCTSBCTSH | |
| SCHEMBL328961 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL4786392 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL30484701 | 0.74 | CTSK (0.53) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL25332754 | 0.74 | CTSK (0.53) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL15821512 | 0.74 | CTSK (0.34) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25320964 | 0.73 | CTSS (0.34) | CTSKCTSS | |
| SCHEMBL9994206 | 0.73 | CTSK (0.38) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151465-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023133174-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2023-07-13 | — | — | WO | disclosed |