Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPC1L1 | Q9UHC9 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25334071 | 1.00 | VDR (0.51) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL17379915 | 0.95 | VDR (0.56) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL21814361 | 0.90 | NPC1L1 (0.62) | VDRUSP2NPC1L1MEN1LMNA | |
| SCHEMBL21814362 | 0.90 | NPC1L1 (0.62) | VDRUSP2NPC1L1MEN1LMNA | |
| SCHEMBL25337296 | 0.89 | NPC1L1 (0.64) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL25336776 | 0.84 | NPC1L1 (0.53) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL25336778 | 0.84 | NPC1L1 (0.53) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL19293667 | 0.84 | GPBAR1 (0.54) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL25334706 | 0.83 | VDR (0.54) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL25334704 | 0.83 | VDR (0.54) | VDRUSP2GPBAR1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789726-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023143398-A1 | STEROID AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |