Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 10/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | VDR | P11473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25336778 | 1.00 | NPC1L1 (0.53) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL25337296 | 0.91 | NPC1L1 (0.64) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL19293662 | 0.86 | VDR (0.54) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL25334704 | 0.85 | VDR (0.54) | NPC1L1USP2VDRGPBAR1CYP2C9 | |
| SCHEMBL25334706 | 0.85 | VDR (0.54) | NPC1L1USP2VDRGPBAR1CYP2C9 | |
| SCHEMBL25334071 | 0.84 | VDR (0.51) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL25334068 | 0.84 | VDR (0.51) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL29397341 | 0.83 | NPC1L1 (0.59) | NPC1L1USP2VDRNPC1MEN1 | |
| SCHEMBL10061280 | 0.81 | GPBAR1 (0.53) | NPC1L1USP2VDRMEN1LMNA | |
| SCHEMBL21561555 | 0.80 | VDR (0.58) | USP2VDRGPBAR1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143399-A1 | STEROID COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 珂阑(上海)医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |