Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | PRCP | P42785 | 3/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25330818 | 1.00 | MDM2 (0.40) | MDM2CYP2C9CYP3A4CYP2C19TSHR | |
| SCHEMBL30545359 | 0.82 | NR1H2 (0.42) | MDM2CYP2C9CYP3A4CYP2C19TSHR | |
| SCHEMBL30545439 | 0.82 | NR1H2 (0.42) | MDM2CYP2C9CYP3A4CYP2C19TSHR | |
| SCHEMBL25331787 | 0.78 | LIPG (0.38) | — | |
| SCHEMBL25331378 | 0.78 | LIPG (0.38) | — | |
| SCHEMBL28885265 | 0.71 | CCR3 (0.34) | ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL22657414 | 0.69 | KMT2A (0.37) | MDM2CYP2C9CYP3A4CYP2C19TSHR | |
| SCHEMBL26113251 | 0.69 | HTR1A (0.31) | — | |
| SCHEMBL25331295 | 0.69 | CYP2C9 (0.40) | CYP2C9CYP3A4CYP2C19TSHRALOX15 | |
| SCHEMBL25332177 | 0.69 | CYP2C9 (0.40) | CYP2C9CYP3A4CYP2C19TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139241-A1 | HETEROCYCLIC COMPOUNDS AS UBIQUITIN SPECIFIC PROTEASE 7 INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2023-07-27 | — | — | WO | disclosed |