SCHEMBL253364

SCHEMBL253364

C=CCOC(=O)CNC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
MAPT P10636 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
ALDH1A1 P00352 5/20 0.37
GAA P10253 2/20 0.37
CYP3A4 P08684 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EPHX2 P34913 1/20 0.35
PPID Q08752 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 2/20 0.33
CASP1 P29466 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15732714 0.98 TSHR (0.42) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL10603014 0.82 TSHR (0.46) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL16329686 0.81 TSHR (0.46) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL3612717 0.81 GAA (0.37) TSHRTDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL1276353 0.80 TSHR (0.47) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL9483470 0.80 TSHR (0.41) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL11148991 0.79 TSHR (0.40) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL28145436 0.79 MAPT (0.43) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL2780857 0.79 TSHR (0.40) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL16691063 0.79 ALDH1A1 (0.41) TSHRTDP1SMN1; SMN2PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2025 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11998631-B2 Dry shampoo mousse composition for hair AMERICAN SPRAYTECH, L.L.C. (US) 2024-06-04 US claimed
CN-117769408-A Dual-phase cosmetic composition and use thereof 巴斯夫欧洲公司 2024-03-26 CN claimed
US-11872296-B2 Preservation compositions CONOPCO, INC. (US) 2024-01-16 US claimed
CN-116942564-A Thickening suspension polymer with wide pH value transparency, preparation method, cleaning agent composition containing thickening suspension polymer, preparation method and application 万华化学集团股份有限公司 2023-10-27 CN claimed
CN-116367814-A Styling shampoo compositions 巴斯夫欧洲公司 2023-06-30 CN claimed
CN-116102693-A Conditioning acrylic acid suspension thickener, preparation method, composition containing conditioning acrylic acid suspension thickener, preparation method and application 万华化学集团股份有限公司 2023-05-12 CN claimed
CN-110964168-B Nonionic silicon-containing aqueous polyurethane dispersions, their preparation and use in hair cleaning 万华化学集团股份有限公司 2021-09-07 CN claimed
CN-106473938-B Detergent composition 花王株式会社 2021-09-03 CN claimed
CN-106473948-B Detergent composition 花王株式会社 2021-08-27 CN claimed
CN-110964168-A Nonionic silicon-containing aqueous polyurethane dispersions, their preparation and use in hair cleaning 上海万华科聚化工科技发展有限公司 2020-04-07 CN claimed
US-20130156715-A1 ANTI-DANDRUFF SHAMPOO CONOPCO, INC., D/B/A UNILEVER 2013-06-20 US claimed
US-20130150338-A1 ANTI-DANDRUFF SHAMPOO CONOPCO, INC., D/B/A UNILEVER 2013-06-13 US claimed
US-20120213725-A1 Surfactant-Polymer Blends LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-08-23 US claimed
WO-2012022553-A1 ANTI-DANDRUFF SHAMPOO UNILEVER PLC (GB) 2012-02-23 WO claimed
WO-2012022552-A1 ANTI-DANDRUFF SHAMPOO UNILEVER PLC (GB) 2012-02-23 WO claimed
WO-2011135582-A2 PHARMACEUTICAL COMPOSITIONS OF DRONEDARONE CADILA HEALTHCARE LIMITED (IN) 2011-11-03 WO claimed
EP-2226100-A1 Composition and process for relaxing or straightening hair L'Oréal (FR) 2010-09-08 EP claimed
US-20100158845-A1 COMPOSITION AND PROCESS FOR RELAXING OR STRAIGHTENING HAIR L'OREAL (FR) 2010-06-24 US claimed
US-5554313-A FOR SOFT HAIR ICI AMERICAS INC. (US) 1996-09-10 US claimed
WO-1996000557-A2 CONDITIONING SHAMPOO CONTAINING INSOLUBLE, NON-VOLATILE SILICONE ICI AMERICAS INC. (US) 1996-01-11 WO claimed