Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 5/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | SPR | P35270 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16835515 | 0.92 | CYP11B2 (0.46) | CYP11B2SCD5ACACBGPR183HDAC2 | |
| SCHEMBL26963320 | 0.90 | GPR183 (0.39) | CYP11B2SCD5ACACBGPR183SPR | |
| SCHEMBL16835523 | 0.89 | CYP11B2 (0.40) | CYP11B2SCD5ACACBUSP30ALDH1A1 | |
| SCHEMBL6114652 | 0.87 | CYP11B2 (0.49) | CYP11B2SCD5ACACBGPR183HDAC2 | |
| SCHEMBL14662248 | 0.85 | CYP11B2 (0.42) | CYP11B2SCD5ACACBUSP30ALDH1A1 | |
| SCHEMBL14297530 | 0.83 | USP2 (0.45) | CYP11B2SCD5ACACBUSP2SMN1; SMN2 | |
| SCHEMBL16835469 | 0.83 | CYP11B2 (0.51) | CYP11B2SCD5ACACBGPR183HDAC2 | |
| SCHEMBL23906185 | 0.82 | CYP11B2 (0.52) | CYP11B2SCD5ACACBGPR183HDAC2 | |
| SCHEMBL25275679 | 0.82 | CYP11B2 (0.52) | CYP11B2SCD5ACACBGPR183HDAC2 | |
| SCHEMBL25309743 | 0.82 | NR1H2 (0.40) | CYP11B2SCD5ACACBGPR183USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | MLLT1, BMI1, MEN1 | CYP11B2 2743/4885SCD5 3736/4885ACACB 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.