SCHEMBL6114652

SCHEMBL6114652

CC(C)(C)OC(=O)N1CCC2(CC(=O)C2)C1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.49
SCD5 Q86SK9 1/20 0.47
ACACB O00763 5/20 0.46
HDAC2 Q92769 2/20 0.44
GPR183 P32249 1/20 0.43
USP30 Q70CQ3 1/20 0.43
USP2 O75604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HDAC1 Q13547 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
SPR P35270 1/20 0.40
GPR119 Q8TDV5 1/20 0.40
RORC P51449 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14662248 0.91 CYP11B2 (0.42) CYP11B2SCD5ACACBUSP30USP2
SCHEMBL904136 0.90 USP2 (0.49) CYP11B2SCD5ACACBGPR183USP2
SCHEMBL16835515 0.90 CYP11B2 (0.46) CYP11B2SCD5ACACBHDAC2GPR183
SCHEMBL25336751 0.87 CYP11B2 (0.45) CYP11B2SCD5ACACBHDAC2GPR183
SCHEMBL6114857 0.87 USP2 (0.43) CYP11B2SCD5ACACBGPR183USP2
SCHEMBL16835469 0.86 CYP11B2 (0.51) CYP11B2SCD5ACACBHDAC2GPR183
SCHEMBL20234376 0.86 CYP11B2 (0.48) CYP11B2SCD5ACACBHDAC2GPR183
SCHEMBL21285082 0.86 USP2 (0.47) CYP11B2SCD5ACACBGPR183USP2
SCHEMBL19273133 0.85 CYP11B2 (0.38) CYP11B2SCD5ACACBHDAC2GPR183
SCHEMBL6868004 0.85 CYP11B2 (0.54) CYP11B2SCD5ACACBHDAC2GPR183

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4413985-B1 PHARMACEUTICAL COMPOUNDS NXERA PHARMA UK LTD (GB) 2026-05-06 EP disclosed
EP-4724435-A1 BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2026-04-15 EP disclosed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
EP-4663190-A2 MUSCARINIC RECEPTOR AGONISTS Nxera Pharma UK Limited (GB) 2025-12-17 EP disclosed
EP-4647431-A1 COMPOUND AND METHOD FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR Gan & lee Pharm Co., Ltd. (CN) 2025-11-12 EP disclosed
US-20250340531-A1 CRYSTALLINE FORMS AND SALTS OF A MUSCARINIC RECEPTOR AGONIST NXERA PHARMA UK LTD (GB) 2025-11-06 US disclosed
EP-4630422-A1 BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-10-15 EP disclosed
EP-4508045-B1 CITRATE SALT FORMS OF A MUSCARINIC RECEPTOR AGONIST NXERA PHARMA UK LTD (GB) 2025-10-01 EP disclosed
US-12398119-B2 Piperazine azaspiro derivatives PFIZER INC. (US) 2025-08-26 US disclosed
EP-4587424-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS Bridgene Biosciences, Inc. (US) 2025-07-23 EP disclosed
WO-2014152114-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-09-25 WO disclosed
US-20140275014-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-09-18 US disclosed
US-20140275014-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-09-18 US disclosed
WO-2014045031-A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2014-03-27 WO disclosed
US-20140045813-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-02-13 US disclosed
US-20140045813-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-02-13 US disclosed
US-20130211087-A1 7-AZA-SPIRO[3,5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-08-15 US disclosed
US-8394787-B2 7-aza-spiro[3.5]nonane-7-carboxylate derivatives, preparation thereof and therapeutic use thereof SANOFI (FR) 2013-03-12 US disclosed
US-20120129830-A1 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-05-24 US disclosed
US-20110319381-A1 DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140275014-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BTK, SYK, LYN CYP11B2 543/4885SCD5 4109/4885ACACB 1326/4885
US-12398119-B2 Piperazine azaspiro derivatives CHRM1, CHRM2, CHRM5 CYP11B2 472/4885SCD5 3472/4885ACACB 4682/4885
US-20140045813-A1 HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS BTK, SYK, LCK CYP11B2 589/4885SCD5 4238/4885ACACB 2355/4885
US-20130211087-A1 7-AZA-SPIRO[3,5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF FAAH, FAAH2, ASAH1 CYP11B2 784/4885SCD5 28/4885ACACB 283/4885
US-20120129830-A1 7-AZA-SPIRO[3.5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF HDAC7, NR3C2, EPOR CYP11B2 102/4885SCD5 3594/4885ACACB 4108/4885
US-20110319381-A1 DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF PRMT9, IDH3B, DHFR CYP11B2 332/4885SCD5 2039/4885ACACB 2951/4885
US-20250340531-A1 CRYSTALLINE FORMS AND SALTS OF A MUSCARINIC RECEPTOR AGONIST CHRM3, CHRM2, CHRM4 CYP11B2 364/4885SCD5 3358/4885ACACB 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.